Biotechnology in Healthcare and Medicine
Biotechnology in Healthcare and Medicine: Overview
This Topic covers sub-topics such as ELISA, Adenosine deaminase Deficiency, Genetically Engineered Insulin, Biotechnology in Medicine, Molecular Diagnosis of Diseases and, Gene Therapy
Important Questions on Biotechnology in Healthcare and Medicine
The use of DNA as a pharmaceutical agent to treat disease is called:
ELISA is used for:
Deficiency of the enzyme ADA causes:
Which of the following protein has been produced by methods of genetic engineering?
An example of gene therapy is
Which of the following types of ELISA contain the following steps?
Antigen binding, Blocking, Primary antibody, Secondary antibody, Enzyme-linked antibody, Substrate, Colorimetric reading (Represented in diagram).
Human protein - anti trypsin is used to treat which disease?
Statement-I: ELISA is based on the principle of antigen-antibody interaction.
Statement-II: Infection by pathogens can be detected by the presence of antigens or by detecting the antibodies synthesised against the pathogens.
Read the following statements and select the correct option from below:
I. Genetically modified crops are more susceptible to natural stress conditions like drought, salinity, etc., as compared to normal crops
II. For the treatment of ADA (adenosine deaminase) deficiency treatment, a functional ADA cDNA was introduced to the lymphocytes of the patient by using lambda phage virus
III. There are more than 3,00,000 rice varieties in India alone
IV. Nitrates, phosphates are easily removed from polluted water in the water treatment plant.
In the PCR technique during the detection of the mutated gene, a single-stranded DNA or RNA, tagged with a radioactive molecule is allowed to hybridise to its complementary DNA in a clone of cells followed by detection using autoradiography. In this statement which of the following term can be used as “radioactive molecule”?
The polymerase chain reaction (PCR) is used to
A probe could be
DNA probes are used in human for
Study the following statements.
A) In germ-line gene therapy functional genes are introduced into somatic cells.
B) Synthetic oligo deoxy nucleosides are used for silencing the disease-causing genes.
C) The transgenic animal product -lactalbumin is used to treat emphysema.
D) Viral vectors are used to send genetically modified DNA by a process called transfection.
The correct statements are:
Match the following and choose the correct option.
| List - I | List - II |
| A) Ovaprim B) Omega-3-fatty acid C) Cadherins D) C- Peptide |
I) Membrane proteins II) Proinsulin III) Reduce cholesterol IV) Synthetic analogue gonadotropin releasing agent V) Exotoxin |
The first gene therapy was given to
Which one of the following application is not related to finger printing?
antitrypsin is used to treat
Identify incorrectly matched scientist and their work:
1) Term biotechnology - Karl Ereky
2) Plasmid was discovered by - Lederberg and Hays
3) Ligases discovered by - Mertz and Davis
4) DNA fingerprinting - French Anderson
5) Tissue culture - Haberlandt
6) Somatic gene therapy (SCID) - Alec Jeffrey and Lalji singh
In human insulin, ___________ is not present in the mature insulin.
